Hereditary Cancer Testing to Know Your Risk

“Accurate knowledge of cancer risk. Actionable direction for patient management”

A scientific advancement that will revolutionize hereditary cancer testing and patient care

By testing with Myriad myRisk™, you’ve just taken an important step in learning whether you are at increased risk for hereditary cancer and the management steps that can lower your risk.

Myriad myRisk hereditary cancer panel combines your genetic information with the personal and family history you give your provider to determine your hereditary cancer risk.

About Myriad’s myRisk™ hereditary cancer test

  • Evaluates clinically actionable gene mutations associated with a focus on eight cancer sites
  • Blends genetic test status AND personal/family cancer history into clinically actionable risk assessment and follow-up

Myriad delivers unsurpassed analysis and interpretation

  • Only Myriad has performed over one million patient genetic tests over 15 years
  • Proprietary methodologies to interpret gene mutations other labs cannot offer

Personal and family history is KEY for

  • Appropriate patient identification for testing
  • Patient management recommendations, especially for those testing negative

A lifetime commitment from Myriad

  • Affordable update testing will be available to those patients who have previously tested with Myriad
  • Myriad commits to being at the forefront of genetics and provide updates to reports as needed

The Myriad myRisk™ test report provides clear and actionable direction for managing patients with both positive AND negative genetic results.

riskScore

When Myriad myRisk was launched in 2013, it became the first test to analyze a patient’s genetic test status and clinical/family history, and represented the next-generation of hereditary cancer testing. With the addition of riskScore, myriad myRisk now provides an even more comprehensive assessment of a patient’s risk for developing breast cancer by blending well-defined highly and moderately penetrant hereditary cancer genes, clinical risk factors, and other genetic markers.

riskScore is a breast cancer risk estimation result that provides some women who have not had breast cancer with a personalized assessment of their 5-year and remaining lifetime breast cancer risk. It can help identify a more accurate and comprehensive lifetime breast cancer risk estimate in individuals who are candidates for hereditary cancer testing. With Myriad’s industry leading accuracy, the level of confidence that riskScore provides is unparalleled.

“For the first time, we’re able to give close to 100% of women an answer as to their risk, whether it’s positive or negative for BRCA1 or one of the other dominant susceptibility alleles, More importantly, for those 90% of women who receive a negative genetic test, they now have an answer to their quantifiable risk that enables them to take proactive measures to either diminish their risk for developing a cancer or to identify that cancer at an early and more curable stage.”
Jonathan M. Lancaster, M.D.

FAQs

Why Myriad myRisk™ Hereditary Cancer?

The Myriad myRisk™ Hereditary Cancer panel does not tell you whether you have cancer. Rather, it detects broken genes associated with eight specific hereditary cancers. Knowing your results enables your healthcare provider and you to take action through increased screening, preventative medicine, or preventative surgery to reduce your risk. Approximately 5% to 10% of all cancers develop because a person inherits a gene that is broken (mutated) in a way that allows cancer to grow. Individuals with these broken genes are far more likely to develop cancer, often at a much earlier age, than the general population. That’s why being tested with myRisk is so important.

Why do I need a management plan if my result is negative?

Just because you test negative for a broken gene does not necessarily mean that you have the same level of risk as the general population. Your or your family’s cancer history increases your risk. The most important thing you can do is give your healthcare provider a complete and accurate family cancer history. Your healthcare provider will work with you to manage your risk. Talking with other family members is very important so that they can take steps to determine their own risk. More information on negative results >

What does a positive result mean?

Learning that you are positive for a broken gene associated with hereditary cancer gives you the power to take action to reduce your risk. Your test report will help by showing options for monitoring and intervention. Your report includes recommendations made by well-established and respected medical societies. These recommendations are for discussion between you and your healthcare provider. The two of you, as well as any loved ones and family you choose, will determine the right course for you. More information on positive results >

How do I read my report?

On the first page, you’ll find a summary of your results. Below the results, you can see which genes, if any, contain a mutation. In the pages that follow, you’ll find information about the specific cancers, their risks, and step you and your health care provider can take to develop a risk management plan that is right for you. More information on myRisk Reports >

Can my health insurance coverage be impacted by the results?

Federal laws (HIPAA and GINA) and laws in most states prohibit discrimination regarding employment eligibility, health benefits, or health insurance premiums based solely on genetic information. Additionally, it is Myriad’s policy that test results are disclosed only to the ordering healthcare professional or designee unless the patient consents otherwise. More information on privacy >

Will my health insurance pay for Myriad myRisk™ testing?

Most insurance arriers cover genetic testing services for hereditary cancer. In fact, the average patient pays less than $11 coinsurance. Most appropriate patients pay $0. More information on insurance and financial assistance >

Why Myriad?

Myriad has the greatest experience and insight in the field of genetic testing for hereditary cancer. Their genetic tests are known for quality and accuracy. Over the past 15 years, Myriad has tested more than one million people. The resulting knowledge base, the highly specialized professional staff, and the commitment to support healthcare providers combine to make Myriad the unquestioned leader in genetic testing for hereditary cancer. Learn more about the Myriad Promise

myRisk Reports Overview

Understanding your report

The test report consists of:

  • Summary and Genetic Test Result (GTR)
  • Personalized Medical Management Tool (MMT) based on professional medical society guidelines
  • Cancer risk info for family when positive

Receiving your results

Your healthcare provider may review your test report with you. Make sure all your questions are answered, and take the time you need to fully understand your results. There are pages in the back of this brochure where you can jot down questions as they occur to you. And don’t hesitate to call your provider if you think of questions at a later time.

Blends genetic information with personal and family history

This is the only hereditary cancer test that provides information about your risk and management based on both your personal/family cancer history and your genetic results. The experts at Myriad, who have tested more than one million patients over 15 years, have the knowledge and experience to bring genetic results and personal and family cancer history together into one fully integrated, personalized report. Please click links for more information about how to understand your Positive results and Negative results

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